Our Research
The science behind every formula
We only use ingredients that have been studied in published, peer-reviewed research. Below you'll find the key studies behind our core ingredients — written in plain English, with full references.
The studies listed below are published in recognised scientific journals and indexed on PubMed, the world's leading medical research database. We reference ingredient-level research — the same evidence used by regulatory bodies to authorise health claims.
Creatine Monohydrate
Creapure® grade — 5g per serving
Creatine is one of the most researched supplements in sports science. It helps your muscles produce energy more quickly during intense exercise — which is why regulators have formally approved the health claim above. It is safe, well-tolerated and effective at the doses we use.
Key studies
Effects of creatine monohydrate timing on resistance training adaptations and body composition after 8 weeks in male and female collegiate athletes
View study →Creatine Supplementation Beyond Athletics: Benefits for Women, Vegans, and Clinical Populations — A Narrative Review
View on PubMed →Ashwagandha KSM-66®
Full-spectrum root extract — 400mg per serving
Ashwagandha is an adaptogenic herb used in traditional medicine for thousands of years. Modern clinical research shows that the KSM-66® extract — the same grade we use — can support the body's normal stress response. It is not approved as a health claim under UK regulation, but the research below is published in peer-reviewed journals and indexed on PubMed.
Key studies
Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study
View on PubMed →Effects of Ashwagandha Supplements on Cortisol, Stress, and Anxiety Levels in Adults: A Systematic Review and Meta-Analysis
View on PubMed →Magnesium Complex
Glycinate + Malate + Taurate — 387mg elemental per serving
Magnesium is involved in over 300 processes in the body. Many people do not get enough from diet alone. We use three forms — glycinate, malate and taurate — because each is absorbed differently, giving broader coverage. These are forms used in the clinical research below.
Key studies
Magnesium Bisglycinate Supplementation in Healthy Adults Reporting Poor Sleep: A Randomized, Placebo-Controlled Trial
View on PubMed →Vitamin D3 + K2
D3 4000IU + K2 MK-7 100µg — liposomal drops
Vitamin D is produced by the skin when exposed to sunlight — but in the UK, many people are deficient, particularly in autumn and winter. Public Health England recommends that everyone consider a vitamin D supplement during these months. We combine it with K2, which helps direct calcium to bones rather than arteries.
Key studies
Infections and Autoimmunity — The Immune System and Vitamin D: A Systematic Review
View study →Public Health England: Vitamin D — advice for all age groups
View NHS guidance →Omega-3 (EPA & DHA)
Fish oil / Krill oil — 1000mg per serving
EPA and DHA are omega-3 fatty acids found in oily fish. They are essential fats, meaning the body cannot make them — they must come from diet or supplements. The British Heart Foundation and NHS both recognise the role of omega-3 in supporting heart health.
Key studies
Effects of Omega-3 Polyunsaturated Fatty Acids on Brain Functions: A Systematic Review
View on PubMed →Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis
View on PubMed →Important: The studies referenced above are ingredient-level research published in peer-reviewed journals. They do not represent claims about specific activGen products. All health claims displayed on this website are authorised under retained EU Regulation No 432/2012 and apply only to the relevant ingredient at the required daily intake. This information is for educational purposes and does not constitute medical advice. Always consult a healthcare professional before starting any supplement.
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